Cargando…

Targeting Astrocyte Signaling Alleviates Cerebrovascular and Synaptic Function Deficits in a Diet-Based Mouse Model of Small Cerebral Vessel Disease

Despite the indispensable role that astrocytes play in the neurovascular unit, few studies have investigated the functional impact of astrocyte signaling in cognitive decline and dementia related to vascular pathology. Diet-mediated induction of hyperhomocysteinemia (HHcy) recapitulates numerous fea...

Descripción completa

Detalles Bibliográficos
Autores principales: Sompol, Pradoldej, Gollihue, Jenna L., Weiss, Blaine E., Lin, Ruei-Lung, Case, Sami L., Kraner, Susan D., Weekman, Erica M., Gant, John C., Rogers, Colin B., Niedowicz, Dana M., Sudduth, Tiffany L., Powell, David K., Lin, Ai-Ling, Nelson, Peter T., Thibault, Olivier, Wilcock, Donna M., Norris, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010459/
https://www.ncbi.nlm.nih.gov/pubmed/36746627
http://dx.doi.org/10.1523/JNEUROSCI.1333-22.2023