Inferring protein fitness landscapes from laboratory evolution experiments

Directed laboratory evolution applies iterative rounds of mutation and selection to explore the protein fitness landscape and provides rich information regarding the underlying relationships between protein sequence, structure, and function. Laboratory evolution data consist of protein sequences sam...

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Detalles Bibliográficos
Autores principales: D’Costa, Sameer, Hinds, Emily C., Freschlin, Chase R., Song, Hyebin, Romero, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010530/
https://www.ncbi.nlm.nih.gov/pubmed/36857380
http://dx.doi.org/10.1371/journal.pcbi.1010956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010530/
https://www.ncbi.nlm.nih.gov/pubmed/36857380
http://dx.doi.org/10.1371/journal.pcbi.1010956

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