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Inferring protein fitness landscapes from laboratory evolution experiments
Directed laboratory evolution applies iterative rounds of mutation and selection to explore the protein fitness landscape and provides rich information regarding the underlying relationships between protein sequence, structure, and function. Laboratory evolution data consist of protein sequences sam...
Autores principales: | D’Costa, Sameer, Hinds, Emily C., Freschlin, Chase R., Song, Hyebin, Romero, Philip A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010530/ https://www.ncbi.nlm.nih.gov/pubmed/36857380 http://dx.doi.org/10.1371/journal.pcbi.1010956 |
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