The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation

DND1 is essential to maintain germ cell identity. Loss of Dnd1 function results in germ cell differentiation to teratomas in some inbred strains of mice or to somatic fates in zebrafish. Using our knock-in mouse line in which a functional fusion protein between DND1 and GFP is expressed from the end...

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Detalles Bibliográficos
Autores principales: Ruthig, Victor A., Hatkevich, Talia, Hardy, Josiah, Friedersdorf, Matthew B., Mayère, Chloé, Nef, Serge, Keene, Jack D., Capel, Blanche
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010562/
https://www.ncbi.nlm.nih.gov/pubmed/36857387
http://dx.doi.org/10.1371/journal.pgen.1010656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010562/
https://www.ncbi.nlm.nih.gov/pubmed/36857387
http://dx.doi.org/10.1371/journal.pgen.1010656

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