Case report: Revascularization failure in NF1-related moyamoya syndrome after selumetinib: A possible pathophysiological correlation?

Neurofibromatosis type 1 (NF1) is a neurocutaneous syndrome caused by pathogenic variants in the NF1 gene, encoding a multidomain inhibitor of Ras activity. Thus, NF1 is considered a RASopathy and drugs targeting the RAS/mitogen-activated protein kinase (MAPK) pathway, such as the MAP kinase (MEK) 1...

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Detalles Bibliográficos
Autores principales: Chelleri, Cristina, Scala, Marcello, De Marco, Patrizia, Traverso, Monica, Ognibene, Marzia, Bruno, Irene, Piccolo, Gianluca, Striano, Pasquale, Severino, Mariasavina, Zara, Federico, Diana, Maria Cristina, Pavanello, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010568/
https://www.ncbi.nlm.nih.gov/pubmed/36923276
http://dx.doi.org/10.3389/fped.2023.1051026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010568/
https://www.ncbi.nlm.nih.gov/pubmed/36923276
http://dx.doi.org/10.3389/fped.2023.1051026

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