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Generation of a transparent killifish line through multiplex CRISPR/Cas9mediated gene inactivation

Body pigmentation is a limitation for in vivo imaging and thus for the performance of longitudinal studies in biomedicine. A possibility to circumvent this obstacle is the employment of pigmentation mutants, which are used in fish species like zebrafish and medaka. To address the basis of aging, the...

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Detalles Bibliográficos
Autores principales: Krug, Johannes, Perner, Birgit, Albertz, Carolin, Mörl, Hanna, Hopfenmüller, Vera L, Englert, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010688/
https://www.ncbi.nlm.nih.gov/pubmed/36820520
http://dx.doi.org/10.7554/eLife.81549