Sensitization of colonic nociceptors by IL-13 is dependent on JAK and p38 MAPK activity

The effective management of visceral pain is a significant unmet clinical need for those affected by gastrointestinal diseases, such as inflammatory bowel disease (IBD). The rational design of novel analgesics requires a greater understanding of the mediators and mechanisms underpinning visceral pai...

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Detalles Bibliográficos
Autores principales: Barker, Katie H., Higham, James P., Pattison, Luke A., Chessell, Iain P., Welsh, Fraser, Smith, Ewan St. J., Bulmer, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010921/
https://www.ncbi.nlm.nih.gov/pubmed/36749569
http://dx.doi.org/10.1152/ajpgi.00280.2022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010921/
https://www.ncbi.nlm.nih.gov/pubmed/36749569
http://dx.doi.org/10.1152/ajpgi.00280.2022

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