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Sensitization of colonic nociceptors by IL-13 is dependent on JAK and p38 MAPK activity
The effective management of visceral pain is a significant unmet clinical need for those affected by gastrointestinal diseases, such as inflammatory bowel disease (IBD). The rational design of novel analgesics requires a greater understanding of the mediators and mechanisms underpinning visceral pai...
Autores principales: | Barker, Katie H., Higham, James P., Pattison, Luke A., Chessell, Iain P., Welsh, Fraser, Smith, Ewan St. J., Bulmer, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010921/ https://www.ncbi.nlm.nih.gov/pubmed/36749569 http://dx.doi.org/10.1152/ajpgi.00280.2022 |
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