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Development and in-vitro evaluation of chitosan and glyceryl monostearate based matrix lipid polymer hybrid nanoparticles (LPHNPs) for oral delivery of itraconazole

Itraconazole (ICZ) is a broad spectrum antifungal drug, but used as second or third line therapy due to its low and erratic oral bioavailability. This work was carried out to prepare and characterize matrix type lipid-polymer hybrid nanoparticles (LPHNPs) for dissolution enhancement of ICZ. LPHNPs w...

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Detalles Bibliográficos
Autores principales: Yousaf, Rimsha, Khan, Muhammad Imran, Akhtar, Muhammad Furqan, Madni, Asadullah, Sohail, Muhammad Farhan, Saleem, Ammara, Irshad, Kanwal, Sharif, Ali, Rana, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010992/
https://www.ncbi.nlm.nih.gov/pubmed/36925532
http://dx.doi.org/10.1016/j.heliyon.2023.e14281