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New perspectives on the induction and acceleration of immune-associated thrombosis by PF4 and VWF

Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a specific protein synthesized from platelet α particles. The combination of PF4 and heparin to form antigenic complexes is an important mechanism in the pathogenesis of heparin-induced thrombocytopenia (HIT), but va...

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Detalles Bibliográficos
Autores principales: Liu, Zhi-Yan, Sun, Min-Xue, Hua, Man-Qi, Zhang, Han-Xu, Mu, Guang-Yan, Zhou, Shuang, Wang, Zhe, Xiang, Qian, Cui, Yi-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011124/
https://www.ncbi.nlm.nih.gov/pubmed/36926331
http://dx.doi.org/10.3389/fimmu.2023.1098665