Transcription of MERVL retrotransposons is required for preimplantation embryo development

Zygotic genome activation (ZGA) is a critical postfertilization step that promotes totipotency and allows different cell fates to emerge in the developing embryo. MERVL (murine endogenous retrovirus-L) is transiently upregulated at the two-cell stage during ZGA. Although MERVL expression is widely u...

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Detalles Bibliográficos
Autores principales: Sakashita, Akihiko, Kitano, Tomohiro, Ishizu, Hirotsugu, Guo, Youjia, Masuda, Harumi, Ariura, Masaru, Murano, Kensaku, Siomi, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011141/
https://www.ncbi.nlm.nih.gov/pubmed/36864102
http://dx.doi.org/10.1038/s41588-023-01324-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011141/
https://www.ncbi.nlm.nih.gov/pubmed/36864102
http://dx.doi.org/10.1038/s41588-023-01324-y

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