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Blockade of endothelin-1 receptor B regulates molecules of the major histocompatibility complex in sickle cell disease
Major Histocompatibility Complex (MHC) molecules have been proposed to play a role in Sickle Cell Disease (SCD) pathophysiology. Endothelial cells express MHC molecules following exposure to cytokines. SCD is characterized, in part, by vascular endothelial cell activation, increased oxidative stress...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011151/ https://www.ncbi.nlm.nih.gov/pubmed/36926339 http://dx.doi.org/10.3389/fimmu.2023.1124269 |