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Blockade of endothelin-1 receptor B regulates molecules of the major histocompatibility complex in sickle cell disease

Major Histocompatibility Complex (MHC) molecules have been proposed to play a role in Sickle Cell Disease (SCD) pathophysiology. Endothelial cells express MHC molecules following exposure to cytokines. SCD is characterized, in part, by vascular endothelial cell activation, increased oxidative stress...

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Detalles Bibliográficos
Autores principales: Inostroza-Nieves, Yaritza, Rivera, Alicia, Romero, José R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011151/
https://www.ncbi.nlm.nih.gov/pubmed/36926339
http://dx.doi.org/10.3389/fimmu.2023.1124269