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TRPA1/M8 agonists upregulate ciliary beating through the pannexin-1 channel in the human nasal mucosa

BACKGROUND: Nasal breathing is important for maintaining physiological respiration. However, airflow in the nasal cavity has an inherent cooling effect and may suppress ciliary beating, an essential frontline defense in the airway. Nasal airflow is thought to be perceived by thermoreceptors for cool...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi Nga, Koga, Yuma, Wakasugi, Tetsuro, Kitamura, Takuro, Suzuki, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011285/
https://www.ncbi.nlm.nih.gov/pubmed/36539563
http://dx.doi.org/10.1007/s11033-022-08201-7