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Proactive Metabolite Testing in Patients on Thiopurine May Yield Long-Term Clinical Benefits in Inflammatory Bowel Disease

BACKGROUND: The thiopurine medications are well established in the treatment of inflammatory bowel disease (IBD). There is significant variation in levels of toxic and therapeutic metabolites. Current data from small or short-term studies support therapeutic drug monitoring (TDM) in assessing azathi...

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Detalles Bibliográficos
Autores principales: Barnes, Alex, Ooi, Soong-Yuan J., Lynch, Kate D., Parthasarathy, Nina, Bishara, Maria, Gounder, Michael, Grafton, Rachel, Leach, Peta, Bampton, Peter, Sechi, Alexandra, Ng, Watson, Connor, Susan, van Langenberg, Daniel, Mountifield, Réme, Andrews, Jane M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011286/
https://www.ncbi.nlm.nih.gov/pubmed/35687221
http://dx.doi.org/10.1007/s10620-022-07556-y