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TOP2A Expression in Pheochromocytoma and Abdominal Paraganglioma: a Marker of Poor Clinical Outcome?

Pheochromocytoma and abdominal paraganglioma (PPGL) are rare neuroendocrine tumors originating from chromaffin cells. Even though only 10–15% of the tumors metastasize, all PPGLs are considered potentially malignant. Topoisomerase 2A (TOP2A) is a protein involved in cell proliferation and has been f...

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Detalles Bibliográficos
Autores principales: Solhusløkk Höse, Karolina, Stenman, Adam, Svahn, Fredrika, Larsson, Catharina, Juhlin, C. Christofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011289/
https://www.ncbi.nlm.nih.gov/pubmed/36656469
http://dx.doi.org/10.1007/s12022-022-09746-w