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Vitamin C transporter SVCT1 serves a physiological role as a urate importer: functional analyses and in vivo investigations

Uric acid, the end product of purine metabolism in humans, is crucial because of its anti-oxidant activity and a causal relationship with hyperuricemia and gout. Several physiologically important urate transporters regulate this water-soluble metabolite in the human body; however, the existence of l...

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Detalles Bibliográficos
Autores principales: Toyoda, Yu, Miyata, Hiroshi, Uchida, Naohiro, Morimoto, Keito, Shigesawa, Ryuichiro, Kassai, Hidetoshi, Nakao, Kazuki, Tomioka, Naoko H., Matsuo, Hirotaka, Ichida, Kimiyoshi, Hosoyamada, Makoto, Aiba, Atsu, Suzuki, Hiroshi, Takada, Tappei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011331/
https://www.ncbi.nlm.nih.gov/pubmed/36749388
http://dx.doi.org/10.1007/s00424-023-02792-1