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Dynamics of histone acetylation during human early embryogenesis

It remains poorly understood about the regulation of gene and transposon transcription during human early embryogenesis. Here, we report that broad H3K27ac domains are genome-widely distributed in human 2-cell and 4-cell embryos and transit into typical peaks in the 8-cell embryos. The broad H3K27ac...

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Detalles Bibliográficos
Autores principales: Wu, Keliang, Fan, Dongdong, Zhao, Han, Liu, Zhenbo, Hou, Zhenzhen, Tao, Wenrong, Yu, Guanling, Yuan, Shenli, Zhu, Xiaoxiao, Kang, Mengyao, Tian, Yong, Chen, Zi-Jiang, Liu, Jiang, Gao, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011383/
https://www.ncbi.nlm.nih.gov/pubmed/36914622
http://dx.doi.org/10.1038/s41421-022-00514-y