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Long-term high-fat diet increases glymphatic activity in the hypothalamus in mice

Obesity affects millions of people worldwide and is associated with an increased risk of cognitive decline. The glymphatic system is a brain-wide metabolic waste clearance system, dysfunction of which is linked to dementia. We herein examined glymphatic transport in mice with long-term obesity induc...

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Detalles Bibliográficos
Autores principales: Delle, Christine, Cankar, Neža, Digebjerg Holgersson, Christian, Hvorup Knudsen, Helle, Schiøler Nielsen, Elise, Kjaerby, Celia, Mori, Yuki, Nedergaard, Maiken, Weikop, Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011420/
https://www.ncbi.nlm.nih.gov/pubmed/36914703
http://dx.doi.org/10.1038/s41598-023-30630-y