The Dengue virus protease NS2B3 cleaves cyclic GMP-AMP synthase to suppress cGAS activation

Dengue virus (DENV) is one of the most prevalent mosquito-transmitted human viruses that causes significant morbidity and mortality worldwide. To persist in the cell and consequently cause disease, DENV is evolved with mechanisms to suppress the induction of type I interferons by antagonizing cGAS-S...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Madhurima, Bhowmik, Debipreeta, Tian, Yuan, He, Huan, Zhu, Fanxiu, Yin, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article Collection: Virology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011430/
https://www.ncbi.nlm.nih.gov/pubmed/36754281
http://dx.doi.org/10.1016/j.jbc.2023.102986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011430/
https://www.ncbi.nlm.nih.gov/pubmed/36754281
http://dx.doi.org/10.1016/j.jbc.2023.102986

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