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The Dengue virus protease NS2B3 cleaves cyclic GMP-AMP synthase to suppress cGAS activation
Dengue virus (DENV) is one of the most prevalent mosquito-transmitted human viruses that causes significant morbidity and mortality worldwide. To persist in the cell and consequently cause disease, DENV is evolved with mechanisms to suppress the induction of type I interferons by antagonizing cGAS-S...
Autores principales: | Bhattacharya, Madhurima, Bhowmik, Debipreeta, Tian, Yuan, He, Huan, Zhu, Fanxiu, Yin, Qian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011430/ https://www.ncbi.nlm.nih.gov/pubmed/36754281 http://dx.doi.org/10.1016/j.jbc.2023.102986 |
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