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Hypoxia enhances interactions between Na(+)/H(+) exchanger isoform 1 and actin filaments via ezrin in pulmonary vascular smooth muscle

Exposure to hypoxia, due to high altitude or chronic lung disease, leads to structural changes in the pulmonary vascular wall, including hyperplasia and migration of pulmonary arterial smooth muscle cells (PASMCs). Previous studies showed that hypoxia upregulates the expression of Na(+)/H(+) exchang...

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Detalles Bibliográficos
Autores principales: Lade, Julie M., Andrade, Manuella R., Undem, Clark, Walker, Jasmine, Jiang, Haiyang, Yun, Xin, Shimoda, Larissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011449/
https://www.ncbi.nlm.nih.gov/pubmed/36926194
http://dx.doi.org/10.3389/fphys.2023.1108304