Biased IL-2 signals induce Foxp3-rich pulmonary lymphoid structures and facilitate long-term lung allograft acceptance in mice

Transplantation of solid organs can be life-saving in patients with end-stage organ failure, however, graft rejection remains a major challenge. In this study, by pre-conditioning with interleukin-2 (IL-2)/anti-IL-2 antibody complex treatment biased toward IL-2 receptor α, we achieved acceptance of...

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Detalles Bibliográficos
Autores principales: Yamada, Yoshito, Nguyen, Tuan Thanh, Impellizzieri, Daniela, Mineura, Katsutaka, Shibuya, Rintaro, Gomariz, Alvaro, Haberecker, Martina, Nilsson, Jakob, Nombela-Arrieta, César, Jungraithmayr, Wolfgang, Boyman, Onur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011523/
https://www.ncbi.nlm.nih.gov/pubmed/36914624
http://dx.doi.org/10.1038/s41467-023-36924-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011523/
https://www.ncbi.nlm.nih.gov/pubmed/36914624
http://dx.doi.org/10.1038/s41467-023-36924-z

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