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Compensatory gene expression potentially rescues impaired brain development in Kit mutant mice

While loss-of-function mutations in the murine dominant white spotting/Kit (W) locus affect a diverse array of cell lineages and organs, the brain, organ with the highest expression show the least number of defective phenotypes. We performed transcriptome analysis of the brains of Kit(W) embryos and...

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Detalles Bibliográficos
Autores principales: Minei, Ryuhei, Aoki, Hitomi, Ogura, Atsushi, Kunisada, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011532/
https://www.ncbi.nlm.nih.gov/pubmed/36914660
http://dx.doi.org/10.1038/s41598-023-30032-0