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Compensatory gene expression potentially rescues impaired brain development in Kit mutant mice
While loss-of-function mutations in the murine dominant white spotting/Kit (W) locus affect a diverse array of cell lineages and organs, the brain, organ with the highest expression show the least number of defective phenotypes. We performed transcriptome analysis of the brains of Kit(W) embryos and...
Autores principales: | Minei, Ryuhei, Aoki, Hitomi, Ogura, Atsushi, Kunisada, Takahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011532/ https://www.ncbi.nlm.nih.gov/pubmed/36914660 http://dx.doi.org/10.1038/s41598-023-30032-0 |
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