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Quantitative proteomic landscape of unstable atherosclerosis identifies molecular signatures and therapeutic targets for plaque stabilization

Atherosclerotic plaque rupture leading to myocardial infarction is a major global health burden. Applying the tandem stenosis (TS) mouse model, which distinctively exhibits the characteristics of human plaque instability/rupture, we use quantitative proteomics to understand and directly compare unst...

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Detalles Bibliográficos
Autores principales: Chen, Yung-Chih, Smith, Meaghan, Ying, Ya-Lan, Makridakis, Manousos, Noonan, Jonathan, Kanellakis, Peter, Rai, Alin, Salim, Agus, Murphy, Andrew, Bobik, Alex, Vlahou, Antonia, Greening, David W., Peter, Karlheinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011552/
https://www.ncbi.nlm.nih.gov/pubmed/36914713
http://dx.doi.org/10.1038/s42003-023-04641-4