TRAK adaptors regulate the recruitment and activation of dynein and kinesin in mitochondrial transport

Mitochondrial transport along microtubules is mediated by Miro1 and TRAK adaptors that recruit kinesin-1 and dynein-dynactin. To understand how these opposing motors are regulated during mitochondrial transport, we reconstitute the bidirectional transport of Miro1/TRAK along microtubules in vitro. W...

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Detalles Bibliográficos
Autores principales: Canty, John T., Hensley, Andrew, Aslan, Merve, Jack, Amanda, Yildiz, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011603/
https://www.ncbi.nlm.nih.gov/pubmed/36914620
http://dx.doi.org/10.1038/s41467-023-36945-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011603/
https://www.ncbi.nlm.nih.gov/pubmed/36914620
http://dx.doi.org/10.1038/s41467-023-36945-8

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