Cholinergic deficits selectively boost cortical intratelencephalic control of striatum in male Huntington’s disease model mice

Huntington’s disease (HD) is a progressive, neurodegenerative disease caused by a CAG triplet expansion in huntingtin. Although corticostriatal dysfunction has long been implicated in HD, the determinants and pathway specificity of this pathophysiology are not fully understood. Here, using a male zQ...

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Detalles Bibliográficos
Autores principales: Pancani, Tristano, Day, Michelle, Tkatch, Tatiana, Wokosin, David L., González-Rodríguez, Patricia, Kondapalli, Jyothisri, Xie, Zhong, Chen, Yu, Beaumont, Vahri, Surmeier, D. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011605/
https://www.ncbi.nlm.nih.gov/pubmed/36914640
http://dx.doi.org/10.1038/s41467-023-36556-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011605/
https://www.ncbi.nlm.nih.gov/pubmed/36914640
http://dx.doi.org/10.1038/s41467-023-36556-3

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