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The ERK activator, BCI, inhibits ciliogenesis and causes defects in motor behavior, ciliary gating, and cytoskeletal rearrangement

MAPK pathways are well-known regulators of the cell cycle, but they have also been found to control ciliary length in a wide variety of organisms and cell types from Caenorhabditis elegans neurons to mammalian photoreceptors through unknown mechanisms. ERK1/2 is a MAP kinase in human cells that is p...

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Detalles Bibliográficos
Autores principales: Dougherty, Larissa L, Dutta, Soumita, Avasthi, Prachee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011610/
https://www.ncbi.nlm.nih.gov/pubmed/36914265
http://dx.doi.org/10.26508/lsa.202301899