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KLHL12 can form large COPII structures in the absence of CUL3 neddylation

CUL3-RING ubiquitin ligases (CRL3s) are involved in various cellular processes through different Bric-a-brac, Tramtrack, and Broad-complex (BTB)–domain proteins. KLHL12, a BTB-domain protein, is suggested to play an essential role in the export of large cargo molecules such as procollagen from the e...

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Detalles Bibliográficos
Autores principales: Moretti, Tamara, Kim, Kyungho, Tuladhar, Astha, Kim, Jinoh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011723/
https://www.ncbi.nlm.nih.gov/pubmed/36652337
http://dx.doi.org/10.1091/mbc.E22-08-0383