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Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia

The primary cilium is a nexus for cell signaling and relies on specific protein trafficking for function. The tubby family protein TULP3 transports integral membrane proteins into cilia through interactions with the intraflagellar transport complex-A (IFT-A) and phosphoinositides. It was previously...

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Detalles Bibliográficos
Autores principales: Palicharla, Vivek Reddy, Hwang, Sun-Hee, Somatilaka, Bandarigoda N., Legué, Emilie, Shimada, Issei S., Familiari, Nicole E., Tran, Vanna M., Woodruff, Jeffrey B., Liem, Karel F., Mukhopadhyay, Saikat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011728/
https://www.ncbi.nlm.nih.gov/pubmed/36652335
http://dx.doi.org/10.1091/mbc.E22-10-0473