Cargando…

FOXO nuclear shuttling dynamics are stimulus-dependent and correspond with cell fate

FOXO transcription factors are regulators of cellular homeostasis linked to increased lifespan and tumor suppression. FOXOs are activated by diverse cell stresses including serum starvation and oxidative stress. FOXO activity is regulated through posttranslational modifications that control shuttlin...

Descripción completa

Detalles Bibliográficos
Autores principales: Lasick, Kathleen A., Jose, Elizabeth, Samayoa, Allison M., Shanks, Lisa, Pond, Kelvin W., Thorne, Curtis A., Paek, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011729/
https://www.ncbi.nlm.nih.gov/pubmed/36735481
http://dx.doi.org/10.1091/mbc.E22-05-0193