Cargando…
FOXO nuclear shuttling dynamics are stimulus-dependent and correspond with cell fate
FOXO transcription factors are regulators of cellular homeostasis linked to increased lifespan and tumor suppression. FOXOs are activated by diverse cell stresses including serum starvation and oxidative stress. FOXO activity is regulated through posttranslational modifications that control shuttlin...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011729/ https://www.ncbi.nlm.nih.gov/pubmed/36735481 http://dx.doi.org/10.1091/mbc.E22-05-0193 |