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Integrated response analysis of pediatric low-grade gliomas during and after targeted therapy treatment
BACKGROUND: Pediatric low-grade gliomas (pLGGs) are the most common central nervous system tumor in children, characterized by RAS/MAPK pathway driver alterations. Genomic advances have facilitated the use of molecular targeted therapies, however, their long-term impact on tumor behavior remains cri...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011805/ https://www.ncbi.nlm.nih.gov/pubmed/36926246 http://dx.doi.org/10.1093/noajnl/vdac182 |