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Integrated response analysis of pediatric low-grade gliomas during and after targeted therapy treatment

BACKGROUND: Pediatric low-grade gliomas (pLGGs) are the most common central nervous system tumor in children, characterized by RAS/MAPK pathway driver alterations. Genomic advances have facilitated the use of molecular targeted therapies, however, their long-term impact on tumor behavior remains cri...

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Detalles Bibliográficos
Autores principales: Tsai, Jessica W, Choi, Jungwhan John, Ouaalam, Hakim, Murillo, Efrain Aguilar, Yeo, Kee Kiat, Vogelzang, Jayne, Sousa, Cecilia, Woods, Jared K, Ligon, Keith L, Warfield, Simon K, Bandopadhayay, Pratiti, Cooney, Tabitha M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011805/
https://www.ncbi.nlm.nih.gov/pubmed/36926246
http://dx.doi.org/10.1093/noajnl/vdac182