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Human DNA polymerase η promotes RNA-templated error-free repair of DNA double-strand breaks

A growing body of evidence indicates that RNA plays a critical role in orchestrating DNA double-strand break repair (DSBR). Recently, we showed that homologous nascent RNA can be used as a template for error-free repair of double-strand breaks (DSBs) in the transcribed genome and to restore the miss...

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Detalles Bibliográficos
Autores principales: Chakraborty, Anirban, Tapryal, Nisha, Islam, Azharul, Sarker, Altaf H., Manohar, Kodavati, Mitra, Joy, Hegde, Muralidhar L., Hazra, Tapas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011834/
https://www.ncbi.nlm.nih.gov/pubmed/36758800
http://dx.doi.org/10.1016/j.jbc.2023.102991