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The unique N-terminal region of Mycobacterium tuberculosis sigma factor A plays a dominant role in the essential function of this protein
SigA (σ(A)) is an essential protein and the primary sigma factor in Mycobacterium tuberculosis (Mtb). However, due to the absence of genetic tools, our understanding of the role and regulation of σ(A) activity and its molecular attributes that help modulate Mtb survival is scant. Here, we generated...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011835/ https://www.ncbi.nlm.nih.gov/pubmed/36690275 http://dx.doi.org/10.1016/j.jbc.2023.102933 |