The unique N-terminal region of Mycobacterium tuberculosis sigma factor A plays a dominant role in the essential function of this protein

SigA (σ(A)) is an essential protein and the primary sigma factor in Mycobacterium tuberculosis (Mtb). However, due to the absence of genetic tools, our understanding of the role and regulation of σ(A) activity and its molecular attributes that help modulate Mtb survival is scant. Here, we generated...

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Detalles Bibliográficos
Autores principales: Singha, Biplab, Behera, Debashree, Khan, Mehak Zahoor, Singh, Nitesh Kumar, Sowpati, Divya Tej, Gopal, Balasubramanian, Nandicoori, Vinay Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011835/
https://www.ncbi.nlm.nih.gov/pubmed/36690275
http://dx.doi.org/10.1016/j.jbc.2023.102933

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