Human Effectors of Acute and Chronic GVHD Overexpress CD83 and Predict Mortality

PURPOSE: Acute and chronic GVHD remain major causes of transplant-related morbidity and mortality (TRM) after allogeneic hematopoietic cell transplantation (alloHCT). We have shown CD83 chimeric antigen receptor (CAR) T cells prevent GVHD and kill myeloid leukemia cell lines. In this pilot study, we...

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Detalles Bibliográficos
Autores principales: Holtan, Shernan G., Savid-Frontera, Constanza, Walton, Kelly, Eaton, Anne A., Demorest, Connor, Hoeschen, Andrea, Zhang, Ling, Reid, Kayla, Kurian, Tony, Sayegh, Zena, Julia, Estefania, Maakaron, Joseph, Bachanova, Veronika, Jurdi, Najla El, MacMillan, Margaret L., Weisdorf, Daniel J., Felices, Martin, Miller, Jeffrey S., Blazar, Bruce R., Davila, Marco L., Betts, Brian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011883/
https://www.ncbi.nlm.nih.gov/pubmed/36622700
http://dx.doi.org/10.1158/1078-0432.CCR-22-2837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011883/
https://www.ncbi.nlm.nih.gov/pubmed/36622700
http://dx.doi.org/10.1158/1078-0432.CCR-22-2837

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