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Intralesional Infiltrations of Cell-Free Filtrates Derived from Human Diabetic Tissues Delay the Healing Process and Recreate Diabetes Histopathological Changes in Healthy Rats

Lower limb ulcers in type-2 diabetic patients are a frequent complication that tributes to amputation and reduces survival. We hypothesized that diabetic healing impairment and other histopathologic hallmarks are mediated by a T2DM-induced tissue priming/metabolic memory that can be transferred from...

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Detalles Bibliográficos
Autores principales: Berlanga-Acosta, Jorge, Fernández-Mayola, Maday, Mendoza-Marí, Yssel, García-Ojalvo, Ariana, Playford, Raymond J., Guillen-Nieto, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012095/
https://www.ncbi.nlm.nih.gov/pubmed/36994347
http://dx.doi.org/10.3389/fcdhc.2021.617741