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Design, Synthesis, and Antiviral Evaluation of Sialic Acid Derivatives as Inhibitors of Newcastle Disease Virus Hemagglutinin-Neuraminidase: A Translational Study on Human Parainfluenza Viruses

[Image: see text] Global infections with viruses belonging to the Paramyxoviridae, such as Newcastle disease virus (NDV) or human parainfluenza viruses (hPIVs), pose a serious threat to animal and human health. NDV-HN and hPIVs-HN (HN hemagglutinin-neuraminidase) share a high degree of similarity in...

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Detalles Bibliográficos
Autores principales: Rota, Paola, La Rocca, Paolo, Bonfante, Francesco, Pagliari, Matteo, Piccoli, Marco, Cirillo, Federica, Ghiroldi, Andrea, Franco, Valentina, Pappone, Carlo, Allevi, Pietro, Anastasia, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012260/
https://www.ncbi.nlm.nih.gov/pubmed/36848501
http://dx.doi.org/10.1021/acsinfecdis.2c00576