Synthesis of Fluorescent Lanthipeptide Cytolysin S Analogues by Late-Stage Sulfamidate Ring Opening

[Image: see text] Nucleophilic ring opening of cyclic sulfamidates derived from amino acids is a common strategy for the synthesis of lanthionine derivatives. In this work, we report the regio-, chemo-, and stereoselective intramolecular S-alkylation of a cysteine residue with N-sulfonyl sulfamidate...

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Detalles Bibliográficos
Autores principales: Mazo, Nuria, Rahman, Imran R., Navo, Claudio D., Peregrina, Jesús M., Busto, Jesús H., van der Donk, Wilfred A., Jiménez-Osés, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012263/
https://www.ncbi.nlm.nih.gov/pubmed/36849130
http://dx.doi.org/10.1021/acs.orglett.3c00122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012263/
https://www.ncbi.nlm.nih.gov/pubmed/36849130
http://dx.doi.org/10.1021/acs.orglett.3c00122

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