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Aminobenzofuran-containing analogues of proximicins exhibit higher antiproliferative activity against human UG-87 glioblastoma cells compared to temozolomide

A new series of proximicin analogues containing a benzofuran moiety as the replacement of the di-furan scaffold of the parent compound were synthesised and evaluated for their anti-proliferative activities against human glioblastoma cells U-87 MG. Proximicins A, B, and C are secondary metabolites pr...

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Detalles Bibliográficos
Autores principales: Shokrzadeh Madieh, Nasrin, Tanna, Sangeeta, Alqurayn, Norah Ahmed, Vaideanu, Alexandra, Schatzlein, Andreas, Brucoli, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012336/
https://www.ncbi.nlm.nih.gov/pubmed/36926006
http://dx.doi.org/10.1039/d3ra00107e