Circ-Ntrk2 acts as a miR-296-5p sponge to activate the TGF-β1/p38 MAPK pathway and promote pulmonary hypertension and vascular remodelling

BACKGROUND: Circular RNAs (circRNAs), a novel class of non-coding RNAs, play an important regulatory role in pulmonary arterial hypertension (PAH); however, the specific mechanism is rarely studied. In this study, we aimed to discover functional circRNAs and investigate their effects and mechanisms...

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Detalles Bibliográficos
Autores principales: Su, Lihuang, Li, Xiuchun, Mao, Xulong, Xu, Tingting, Zhang, Yiying, Li, Shini, Zhu, Xiayan, Wang, Liangxing, Yao, Dan, Wang, Jian, Huang, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012448/
https://www.ncbi.nlm.nih.gov/pubmed/36915149
http://dx.doi.org/10.1186/s12931-023-02385-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012448/
https://www.ncbi.nlm.nih.gov/pubmed/36915149
http://dx.doi.org/10.1186/s12931-023-02385-7

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