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P-15 promotes chondrocyte proliferation in osteoarthritis by regulating SFPQ to target the Akt-RUNX2 axis

BACKGROUND: The disruption of chondrocyte proliferation and differentiation is a critical event during the process of joint injury in osteoarthritis (OA). P-15 peptides could bind to integrin receptors on various precursor cells, promote cell adhesion, release growth factors, and promote the differe...

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Detalles Bibliográficos
Autores principales: Li, Yuanli, Nie, Junlan, Deng, Changgong, Li, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012506/
https://www.ncbi.nlm.nih.gov/pubmed/36915153
http://dx.doi.org/10.1186/s13018-023-03658-z