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P-15 promotes chondrocyte proliferation in osteoarthritis by regulating SFPQ to target the Akt-RUNX2 axis
BACKGROUND: The disruption of chondrocyte proliferation and differentiation is a critical event during the process of joint injury in osteoarthritis (OA). P-15 peptides could bind to integrin receptors on various precursor cells, promote cell adhesion, release growth factors, and promote the differe...
Autores principales: | Li, Yuanli, Nie, Junlan, Deng, Changgong, Li, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012506/ https://www.ncbi.nlm.nih.gov/pubmed/36915153 http://dx.doi.org/10.1186/s13018-023-03658-z |
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