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Magnesium hydroxide versus macrogol/electrolytes in the prevention of opioid-induced constipation in incurable cancer patients: study protocol for an open-label, randomized controlled trial (the OMAMA study)

BACKGROUND: Opioid-induced constipation (OIC) is a common symptom in cancer patients treated with opioids with a prevalence of up to 59%. International guidelines recommend standard laxatives such as macrogol/electrolytes and magnesium hydroxide to prevent OIC, although evidence from randomized cont...

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Detalles Bibliográficos
Autores principales: Kistemaker, K.R.J., de Graeff, A., Crul, M., de Klerk, G., van de Ven, P.M., van der Meulen, M.P., van Zuylen, L., Steegers, M.A.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012532/
https://www.ncbi.nlm.nih.gov/pubmed/36915062
http://dx.doi.org/10.1186/s12904-023-01143-2