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Macrophage-Derived MMP-9 and MMP-2 are Closely Related to the Rupture of the Fibrous Capsule of Hepatocellular Carcinoma Leading to Tumor Invasion

BACKGROUND: Hepatocellular carcinoma (HCC) is an aggressive tumor with a poor clinical prognosis. Rupture of the fibrous capsule (FC) is a very important clinical phenomenon in the invasion and metastasis of HCC. FC is mainly composed of type I collagen (COL1A1). However, it is not clear what caused...

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Detalles Bibliográficos
Autores principales: Cui, Quanwei, Wang, Xuben, Zhang, Yongwei, Shen, Yiqing, Qian, Yeben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012540/
https://www.ncbi.nlm.nih.gov/pubmed/36918768
http://dx.doi.org/10.1186/s12575-023-00196-0