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Therapeutic potential of ADAM10 modulation in Alzheimer’s disease: a review of the current evidence

Alzheimer’s disease (AD), the most common neurodegenerative disease worldwide, is caused by loss of neurons and synapses in central nervous system. Several causes for neuronal death in AD have been introduced, the most important of which are extracellular amyloid β (Aβ) accumulation and aggregated t...

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Detalles Bibliográficos
Autores principales: Khezri, Mohammad Rafi, Mohebalizadeh, Mehdi, Ghasemnejad-Berenji, Morteza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012555/
https://www.ncbi.nlm.nih.gov/pubmed/36918870
http://dx.doi.org/10.1186/s12964-023-01072-w