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Attenuation of IFN signaling due to m(6)A modification of the host epitranscriptome promotes EBV lytic reactivation

BACKGROUND: Reactivation of Epstein Barr virus (EBV) leads to modulation of the viral and cellular epitranscriptome. N6-methyladenosine (m(6)A) modification is a type of RNA modification that regulates metabolism of mRNAs. Previous reports demonstrated that m(6)A modification affects the stability a...

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Detalles Bibliográficos
Autores principales: Bose, Dipayan, Lin, Xiang, Gao, Le, Wei, Zhi, Pei, Yonggang, Robertson, Erle S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012557/
https://www.ncbi.nlm.nih.gov/pubmed/36918845
http://dx.doi.org/10.1186/s12929-023-00911-9