Cargando…

Autophagy is a novel pathway for neurofilament protein degradation in vivo

How macroautophagy/autophagy influences neurofilament (NF) proteins in neurons, a frequent target in neurodegenerative diseases and injury, is not known. NFs in axons have exceptionally long half-lives in vivo enabling formation of large stable supporting networks, but they can be rapidly degraded d...

Descripción completa

Detalles Bibliográficos
Autores principales: Rao, Mala V., Darji, Sandipkumar, Stavrides, Philip H., Goulbourne, Chris N., Kumar, Asok, Yang, Dun-Sheng, Yoo, Lang, Peddy, James, Lee, Ju-Hyun, Yuan, Aidong, Nixon, Ralph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012948/
https://www.ncbi.nlm.nih.gov/pubmed/36131358
http://dx.doi.org/10.1080/15548627.2022.2124500